Assay Detail
Binding
CHEMBL5140971
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at Androgen receptor in human MDA-kb2 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | MDA-kb2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Strategies to Target the Androgen Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.68 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL391548 | — | — | 1 | 9.70 |
| CHEMBL399887 | — | — | 1 | 7.92 |
| CHEMBL1085593 | — | — | 1 | 7.42 |
| CHEMBL5208304 | — | — | 1 | 7.35 |
| CHEMBL470204 | — | — | 1 | 7.24 |
| CHEMBL490956 | — | — | 1 | 7.11 |
| CHEMBL458084 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL391548 | — | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL399887 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL1085593 | — | IC50 | = | 38.0 | nM | 7.42 |
| CHEMBL5208304 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL470204 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL490956 | — | IC50 | = | 78.0 | nM | 7.11 |
| CHEMBL458084 | — | IC50 | = | 90.0 | nM | 7.05 |