Assay Detail
Binding
CHEMBL5141190
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Inhibition of KDM4C (unknown origin) measured by AlphaScreen assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent Advances with KDM4 Inhibitors and Potential Applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.92 | 8.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5203487 | — | — | 1 | 8.66 |
| CHEMBL5203308 | — | — | 1 | 7.48 |
| CHEMBL278315 | GELDANAMYCIN | 2.0 | 1 | 6.16 |
| CHEMBL383824 | ALVESPIMYCIN | 2.0 | 1 | 6.16 |
| CHEMBL109480 | TANESPIMYCIN | 3.0 | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5203487 | — | IC50 | = | 2.2 | nM | 8.66 |
| CHEMBL5203308 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL278315 | GELDANAMYCIN | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL383824 | ALVESPIMYCIN | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL109480 | TANESPIMYCIN | IC50 | = | 700.0 | nM | 6.16 |