Assay Detail
Binding
CHEMBL5147286
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate incubated for 10 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Polyphenolic compounds: Synthesis, assessment of antimicrobial effect and enzymes inhibition against important medicinal enzymes with computational details.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.59 | 5.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1831286 | — | — | 1 | 5.63 |
| CHEMBL5174709 | — | — | 1 | 5.55 |
| CHEMBL287556 | KOJIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1831286 | — | IC50 | = | 2320.0 | nM | 5.63 |
| CHEMBL5174709 | — | IC50 | = | 2830.0 | nM | 5.55 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 3.49 | ug.mL-1 | - |