Assay Detail
Functional
CHEMBL5151201
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Anticonvulsant activity in MES induced Kunming mouse model of seizure assessed as EC50 in plasma
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.00 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5180351 | — | — | 1 | 7.30 |
| CHEMBL41355 | EZOGABINE | 4.0 | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5180351 | — | EC50 | = | 50.0 | nM | 7.30 |
| CHEMBL41355 | EZOGABINE | EC50 | = | 20040.0 | nM | 4.70 |