Assay Detail
Binding
CHEMBL5161531
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of coagulation factor Xa (unknown origin) using chromogenic substrate incubated for 7 min in presence of antithrombin by absorbance based assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemical synthesis and pharmacological properties of heparin pentasaccharide analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.98 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5207683 | — | — | 1 | 7.05 |
| CHEMBL5203721 | — | — | 1 | 7.02 |
| CHEMBL1200644 | FONDAPARINUX SODIUM | 4.0 | 1 | 7.00 |
| CHEMBL5176075 | — | — | 1 | 6.97 |
| CHEMBL5180987 | — | — | 1 | 6.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5207683 | — | IC50 | = | 88.8 | nM | 7.05 |
| CHEMBL5203721 | — | IC50 | = | 94.7 | nM | 7.02 |
| CHEMBL1200644 | FONDAPARINUX SODIUM | IC50 | = | 99.6 | nM | 7.00 |
| CHEMBL5176075 | — | IC50 | = | 108.1 | nM | 6.97 |
| CHEMBL5180987 | — | IC50 | = | 141.08 | nM | 6.85 |