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Assay Detail

CHEMBL5216038

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitrypanosomal activity against bloodstream Trypanosoma cruzi Y strain trypomastigote assessed as reduction in parasite viability incubated for 24 hrs by Neubauer chamber based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma cruzi
Confidence 1 — Organism
Curated By Autocuration

Target

Trypanosoma cruzi (CHEMBL368)
Type ORGANISM
Organism Trypanosoma cruzi

Publication

Cysteine proteases as potential targets for anti-trypanosomatid drug discovery.
Judice WAS, Ferraz LS, Lopes RM, Vianna LDS, Siqueira FDS, Di Iorio JF, Dalzoto LAM, Trujilho MNR, Santos TDR, Machado MFM, Rodrigues T.
Bioorg Med Chem (2021) 46 : 116365 -116365
PubMed 34419821 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.69 4.69

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL286722 1 4.69

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL286722 IC50 = 20400.0 nM 4.69