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Assay Detail

CHEMBL5224378

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Functional
Anticancer activity against human T47D cells assessed as cell growth inhibition incubated for 24 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type T47D
Confidence 1 — Organism
Curated By Autocuration

Target

T47D (CHEMBL614361)
Type CELL-LINE
Organism Homo sapiens

Publication

Evolution of 3-(4-hydroxyphenyl)indoline-2-one as a scaffold for potent and selective anticancer activity.
Boudreau MW, Hergenrother PJ.
RSC Med Chem (2022) 13 : 711 -725
PubMed 35814932 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.47 7.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5266426 1 7.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5266426 IC50 = 34.0 nM 7.47