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Assay Detail

CHEMBL5225339

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to SIGMAR1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sigma non-opioid intracellular receptor 1 (CHEMBL287)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The Emerging Landscape of Small-Molecule Therapeutics for the Treatment of Huntington's Disease.
Ahamad S, Bhat SA.
J Med Chem (2022) 65 : 15993 -16032
PubMed 36490325 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.66 8.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL305881 1 8.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL305881 Ki = 2.2 nM 8.66