Assay Detail

CHEMBL5231984

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Functional

Cytotoxicity against human T47D cells assessed as reduction in cell viability after 48 hrs by MTT assay

ChEMBL ↗

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Target

T47D (CHEMBL614361) ↗

Open DB target context

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T47D (CHEMBL614361) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target T47D

CHEMBL614361

Anchored from Assay target.

Protein identity T47D

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	T47D
Confidence	1 — Organism
Curated By	Autocuration

Target

T47D (CHEMBL614361) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

A review: Biologically active 3,4-heterocycle-fused coumarins.

Salehian F, Nadri H, Jalili-Baleh L, Youseftabar-Miri L, Abbas Bukhari SN, Foroumadi A, Tüylü Küçükkilinç T, Sharifzadeh M, Khoobi M.
Eur J Med Chem (2021) 212 : 113034 -113034
PubMed 33276991 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	10.10	10.10

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL373114	LAMELLARIN D	—	1	10.10

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL373114	LAMELLARIN D	IC50	=	0.08	nM	10.10