Assay Detail
Binding
CHEMBL5235487
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human recombinant FPR1 stably transfected in Flp-In-CHO cells assessed as ERK1/2 phosphorylation incubated for 1 hr by Alphascreen fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Flp-In-CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.00 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5284927 | — | — | 1 | 6.10 |
| CHEMBL4588649 | — | — | 1 | 6.00 |
| CHEMBL5283998 | — | — | 1 | 5.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5284927 | — | EC50 | = | 794.33 | nM | 6.10 |
| CHEMBL4588649 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL5283998 | — | EC50 | = | 1258.93 | nM | 5.90 |