Assay Detail
Binding
CHEMBL5235494
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Agonist activity at FPR2 (unknown origin) assessed as increase in calcium flux
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 9.61 | 10.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5271637 | — | — | 1 | 10.70 |
| CHEMBL4794375 | — | — | 1 | 9.60 |
| CHEMBL5275581 | — | — | 1 | 9.54 |
| CHEMBL5288663 | — | — | 1 | 8.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5271637 | — | EC50 | = | 0.02 | nM | 10.70 |
| CHEMBL4794375 | — | EC50 | = | 0.25 | nM | 9.60 |
| CHEMBL5275581 | — | EC50 | = | 0.29 | nM | 9.54 |
| CHEMBL5288663 | — | EC50 | = | 2.5 | nM | 8.60 |