Assay Detail

CHEMBL5245698

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiproliferative activity against human NB-4 cells

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

NB-4 (CHEMBL614188) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

NB-4 (CHEMBL614188) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NB-4

CHEMBL614188

Anchored from Assay target.

Protein identity NB-4

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	NB-4
Confidence	1 — Organism
Curated By	Autocuration

Target

NB-4 (CHEMBL614188) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Recent developments of small molecules targeting RNA m<sup>6</sup>A modulators.

Gu J, Xu J, You Q, Guo X.
Eur J Med Chem (2020) 196 : 112325 -112325
PubMed 32330741 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.10	6.10

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4567838	—	—	1	6.10

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4567838	—	IC50	=	800.0	nM	6.10