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Assay Detail

CHEMBL5246281

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitrypanosomal activity against Trypanosoma cruzi Y strain amastigotes incubated for 24 hrs by microscopy analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trypanosoma cruzi
Confidence 1 — Organism
Curated By Autocuration

Target

Trypanosoma cruzi (CHEMBL368)
Type ORGANISM
Organism Trypanosoma cruzi

Publication

The role of imidazole and benzimidazole heterocycles in Chagas disease: A review.
Beltran-Hortelano I, Alcolea V, Font M, Pérez-Silanes S.
Eur J Med Chem (2020) 206 : 112692 -112692
PubMed 32818869 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.05 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1236677 1 6.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1236677 IC50 = 900.0 nM 6.05