Assay Detail
ADMET
CHEMBL5255415
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Mixed type inhibition of CYP2A6 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of coumarin derivatives as selective CYP2A6 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.18 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL502746 | — | — | 1 | 7.30 |
| CHEMBL416 | METHOXSALEN | 4.0 | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL502746 | — | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL416 | METHOXSALEN | Ki | = | 90.0 | nM | 7.05 |