Assay Detail
Binding
CHEMBL5262840
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to FABP4 (unknown origin) assessed as inhibition constant
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Fatty acid-binding protein, adipocyte (CHEMBL2083) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 7.23 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5272139 | — | — | 1 | 10.00 |
| CHEMBL3814634 | — | — | 1 | 7.52 |
| CHEMBL3813892 | — | — | 1 | 7.00 |
| CHEMBL3814575 | — | — | 1 | 6.92 |
| CHEMBL247920 | — | — | 1 | 6.80 |
| CHEMBL5282369 | — | — | 1 | 5.15 |
| CHEMBL5286983 | — | — | 1 | - |
| CHEMBL5285281 | — | — | 1 | - |
| CHEMBL5276452 | — | — | 1 | - |
| CHEMBL1586017 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5272139 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL3814634 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL3813892 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL3814575 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL247920 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL5282369 | — | Ki | = | 7100.0 | nM | 5.15 |
| CHEMBL5286983 | — | Ki | = | 340430.0 | nM | - |
| CHEMBL5285281 | — | Ki | = | 323360.0 | nM | - |
| CHEMBL5276452 | — | Ki | = | 377400.0 | nM | - |
| CHEMBL1586017 | — | Ki | > | 1400.0 | nM | - |