Compound Detail
CHEMBL5272139
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Basic Information
| ChEMBL ID | CHEMBL5272139 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JWFBAMFIGZEDER-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
436.7
MW (Da)
5.14
ALogP
4
HBA
1
HBD
66.3
PSA (Ų)
0.62
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 10.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty acid-binding protein, adipocyte CHEMBL2083 | Ki | 10.0 | 10.0 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty acid-binding protein, adipocyte | Ki | = | 0.1 | nM | 10.0 | Binding affinity to FABP4 (unknown origin) assessed as inhibition constant | 28738306 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28738306 | 10.1016/j.ejmech.2017.07.022 | Fatty acid-binding protein, adipocyte | 1 |
Data from ChEMBL 36 via Core Engine