Assay Detail
Binding
CHEMBL5262865
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human SYK using 5-Fluo-Ahx-GAPDYENLQELNKK-Amid as substrate in presence of ATP by microfluidic mobility shift assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 9.10 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3416026 | — | — | 1 | 9.10 |
| CHEMBL3965225 | — | — | 1 | 9.10 |
| CHEMBL3932871 | — | — | 1 | 9.10 |
| CHEMBL3416027 | — | — | 1 | 9.10 |
| CHEMBL3962214 | — | — | 1 | 9.10 |
| CHEMBL3967315 | — | — | 1 | 9.10 |
| CHEMBL3893313 | — | — | 1 | 9.10 |
| CHEMBL3930413 | — | — | 1 | 9.10 |
| CHEMBL3962915 | — | — | 1 | 9.10 |
| CHEMBL3899231 | — | — | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3416026 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3965225 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3932871 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3416027 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3962214 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3967315 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3893313 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3930413 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3962915 | — | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL3899231 | — | IC50 | = | 0.8 | nM | 9.10 |