Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5262929

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of beta catenin/Tcf4 (unknown origin) protein protein interaction
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

TCF4-CTNNB1 complex (CHEMBL3885541)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds.
Cascioferro S, Parrino B, Spanò V, Carbone A, Montalbano A, Barraja P, Diana P, Cirrincione G.
Eur J Med Chem (2017) 142 : 328 -375
PubMed 28851503 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.80 7.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5285550 1 7.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5285550 IC50 = 16.0 nM 7.80