Compound Detail
CHEMBL5285550
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Basic Information
| ChEMBL ID | CHEMBL5285550 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WIFUUUZACLMGEW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
383.4
MW (Da)
1.37
ALogP
8
HBA
0
HBD
82.2
PSA (Ų)
0.61
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| TCF4-CTNNB1 complex CHEMBL3885541 | IC50 | 7.8 | 7.8 | 16.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| TCF4-CTNNB1 complex | IC50 | = | 16.0 | nM | 7.8 | Inhibition of beta catenin/Tcf4 (unknown origin) protein protein interaction | 28851503 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28851503 | 10.1016/j.ejmech.2017.08.009 | TCF4-CTNNB1 complex | 1 |
| 28851503 | 10.1016/j.ejmech.2017.08.009 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine