Assay Detail
Functional
CHEMBL5263049
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Trypanocidal activity against Trypanosoma brucei Lab 110 strain
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Polyamine-based analogs and conjugates as antikinetoplastid agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.80 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86281 | — | — | 1 | 7.00 |
| CHEMBL62048 | — | — | 1 | 6.30 |
| CHEMBL86096 | — | — | 1 | 6.00 |
| CHEMBL40258 | — | — | 1 | 5.00 |
| CHEMBL310207 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86281 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL62048 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL86096 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL40258 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL310207 | — | IC50 | = | 20000.0 | nM | 4.70 |