Assay Detail
Binding
CHEMBL5263471
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and measured after 10 mins in presence of NADPH by scintillation counting analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Gallus gallus |
| Tissue | Liver |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Amphiphilic glycoconjugates as potential anti-cancer chemotherapeutics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.81 | 4.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5271377 | — | — | 1 | 4.81 |
| CHEMBL5266900 | — | — | 1 | 4.81 |
| CHEMBL5269517 | — | — | 1 | 4.81 |
| CHEMBL5274276 | — | — | 1 | 4.81 |
| CHEMBL5283434 | — | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5271377 | — | IC50 | = | 15600.0 | nM | 4.81 |
| CHEMBL5266900 | — | IC50 | = | 15600.0 | nM | 4.81 |
| CHEMBL5269517 | — | IC50 | = | 15600.0 | nM | 4.81 |
| CHEMBL5274276 | — | IC50 | = | 15600.0 | nM | 4.81 |
| CHEMBL5283434 | — | IC50 | = | 15600.0 | nM | 4.81 |