Assay Detail
Functional
CHEMBL5318488
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma cruzi Tulahuen amastigotes infected in monkey LLC-MK2 cells assessed as reduction in amastigotes per 100 cells by cell counting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma cruzi |
| Cell Type | LLC-MK2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel Diarylthioether Compounds as Agents for the Treatment of Chagas Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.60 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3431410 | — | — | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3431410 | — | IC50 | = | 251.19 | nM | 6.60 |