Assay Detail
Binding
CHEMBL5318931
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Inhibition of DAPK1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting Death-Associated Protein Kinases for Treatment of Human Diseases: Recent Advances and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.98 | 6.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5407750 | — | — | 1 | 6.61 |
| CHEMBL5433785 | — | — | 1 | 6.43 |
| CHEMBL5398489 | — | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5407750 | — | IC50 | = | 247.0 | nM | 6.61 |
| CHEMBL5433785 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL5398489 | — | IC50 | = | 13000.0 | nM | 4.89 |