Compound Detail
CHEMBL5407750
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5407750 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MAIMRLBVWRGKMP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
431.5
MW (Da)
3.07
ALogP
7
HBA
2
HBD
92.0
PSA (Ų)
0.47
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.61
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Death-associated protein kinase 1 CHEMBL2558 | IC50 | 6.61 | 6.61 | 247.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Death-associated protein kinase 1 | IC50 | = | 247.0 | nM | 6.61 | Inhibition of DAPK1 (unknown origin) | 36645394 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36645394 | 10.1021/acs.jmedchem.2c01606 | Death-associated protein kinase 1 | 1 |
Data from ChEMBL 36 via Core Engine