Assay Detail
Binding
CHEMBL5318937
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DAPK1 (1 to 285 residues) (unknown origin) expressed in Escherichia coli using KKLNRTLSFAEPG as substrate in presence of ATP by fluoro-spark kinase assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting Death-Associated Protein Kinases for Treatment of Human Diseases: Recent Advances and Future Directions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.50 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL294264 | PURPURIN | — | 1 | 6.05 |
| CHEMBL55814 | ATHRAQUINONES A | — | 1 | 5.44 |
| CHEMBL5028838 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL294264 | PURPURIN | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL55814 | ATHRAQUINONES A | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL5028838 | — | IC50 | = | 9600.0 | nM | 5.02 |