Assay Detail
ADMET
CHEMBL5327944
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CYP3A4 using midazolam as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.08 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5422616 | — | — | 1 | 5.08 |
| CHEMBL5405569 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5422616 | — | IC50 | = | 8300.0 | nM | 5.08 |
| CHEMBL5405569 | — | IC50 | > | 30000.0 | nM | - |