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Assay Detail

CHEMBL5328219

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ADMET
Inhibition of human CYP2C9 by LC-MS/MS analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cytochrome P450 2C9 (CHEMBL3397)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models.
Zhu W, Liu X, Li Q, Gao F, Liu T, Chen X, Zhang M, Aliper A, Ren F, Ding X, Zhavoronkov A.
Bioorg Med Chem (2023) 91 : 117414 -117414
PubMed 37467565 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.30 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5394880 1 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5394880 IC50 = 50000.0 nM 4.30