Assay Detail
Functional
CHEMBL5332810
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Cytotoxicity against human T47D cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.54 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5432925 | — | — | 1 | 6.08 |
| CHEMBL5404116 | — | — | 1 | 5.45 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5432925 | — | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL5404116 | — | IC50 | = | 3570.0 | nM | 5.45 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 8120.0 | nM | 5.09 |