Assay Detail
Binding
CHEMBL5337909
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at glucocorticoid receptor (unknown origin) expressed in K562 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The medicinal chemistry evolution of antibody-drug conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.62 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5433271 | — | — | 1 | 8.52 |
| CHEMBL2040682 | CICLESONIDE | 4.0 | 1 | 7.66 |
| CHEMBL5439877 | — | — | 1 | 7.48 |
| CHEMBL5417330 | — | — | 1 | 7.37 |
| CHEMBL5435559 | — | — | 1 | 7.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5433271 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL2040682 | CICLESONIDE | EC50 | = | 22.0 | nM | 7.66 |
| CHEMBL5439877 | — | EC50 | = | 33.0 | nM | 7.48 |
| CHEMBL5417330 | — | EC50 | = | 43.0 | nM | 7.37 |
| CHEMBL5435559 | — | EC50 | = | 84.0 | nM | 7.08 |