Assay Detail
Binding
CHEMBL5337967
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Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glucose-induced degradation protein 4 homolog (CHEMBL5169174) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 9 | 5.68 | 7.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5177469 | — | — | 1 | 7.09 |
| CHEMBL5393907 | — | — | 1 | 6.52 |
| CHEMBL5411984 | — | — | 1 | 6.30 |
| CHEMBL5197897 | — | — | 1 | 5.64 |
| CHEMBL5435433 | — | — | 1 | 5.57 |
| CHEMBL5405098 | — | — | 1 | 5.47 |
| CHEMBL5414824 | — | — | 1 | 5.05 |
| CHEMBL5426366 | — | — | 1 | 4.82 |
| CHEMBL5411414 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5177469 | — | Kd | = | 81.0 | nM | 7.09 |
| CHEMBL5393907 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL5411984 | — | Kd | = | 500.0 | nM | 6.30 |
| CHEMBL5197897 | — | Kd | = | 2300.0 | nM | 5.64 |
| CHEMBL5435433 | — | Kd | = | 2700.0 | nM | 5.57 |
| CHEMBL5405098 | — | Kd | = | 3400.0 | nM | 5.47 |
| CHEMBL5414824 | — | Kd | = | 9000.0 | nM | 5.05 |
| CHEMBL5426366 | — | Kd | = | 15000.0 | nM | 4.82 |
| CHEMBL5411414 | — | Kd | = | 24000.0 | nM | 4.62 |