Assay Detail
Functional
CHEMBL5339946
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anti-necroptotic activity in FADD-deficient human Jurkat cells assessed as reduction in cell growth preincubated for 30 mins followed by TNFalpha stimulation incubated overnight by CellTiter-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From (Tool)Bench to Bedside: The Potential of Necroptosis Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.73 | 5.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL188381 | GW806742X | — | 1 | 5.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL188381 | GW806742X | EC50 | = | 1850.0 | nM | 5.73 |