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Assay Detail

CHEMBL5348485

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of guinea pig leukotriene D4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cysteinyl leukotriene receptor 1 (CHEMBL5645)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Treatment of allergy: Overview of synthetic anti-allergy small molecules in medicinal chemistry.
Zhang S, Liu Y, Javeed A, Jian C, Sun J, Wu S, Han B.
Eur J Med Chem (2023) 249 : 115151 -115151
PubMed 36731273 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.58 6.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4463974 1 6.64
CHEMBL20403 ZD-2138 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4463974 IC50 = 229.0 nM 6.64
CHEMBL20403 ZD-2138 IC50 = 300.0 nM 6.52