Assay Detail
Binding
CHEMBL5348525
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Binding affinity to CECR2 (unknown origin) assessed as dissociation constant by site-directed competition binding assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Chromatin remodeling regulator CECR2 (CHEMBL3108639) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A novel pan-selective bromodomain inhibitor for epigenetic drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.06 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3133807 | — | — | 1 | 8.10 |
| CHEMBL5439294 | — | — | 1 | 6.01 |
| CHEMBL5398641 | — | — | 1 | - |
| CHEMBL5433870 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3133807 | — | Kd | = | 8.0 | nM | 8.10 |
| CHEMBL5439294 | — | Kd | = | 970.0 | nM | 6.01 |
| CHEMBL5398641 | — | Kd | > | 10000.0 | nM | - |
| CHEMBL5433870 | — | Kd | > | 10000.0 | nM | - |