Assay Detail
Functional
CHEMBL5349949
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Antiviral activity against Cowpox virus infected in Vero cells measured after 4 days by colorimetric assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cowpox virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 4.83 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5434267 | — | — | 1 | 5.70 |
| CHEMBL121690 | — | — | 1 | 5.46 |
| CHEMBL152 | CIDOFOVIR ANHYDROUS | 4.0 | 1 | 4.35 |
| CHEMBL346387 | — | — | 1 | 4.33 |
| CHEMBL5405806 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5434267 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL121690 | — | EC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL152 | CIDOFOVIR ANHYDROUS | EC50 | = | 44700.0 | nM | 4.35 |
| CHEMBL346387 | — | EC50 | = | 46200.0 | nM | 4.33 |
| CHEMBL5405806 | — | EC50 | = | 48300.0 | nM | 4.32 |