Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5405806

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Nc1ccn(C[C@@H]2COP(=O)(O)CO2)c(=O)n1

Basic Information

ChEMBL ID CHEMBL5405806
Phase Preclinical
Structure Type MOL
InChI Key YXQUGSXUDFTPLL-ZCFIWIBFSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

261.2
MW (Da)
-0.62
ALogP
7
HBA
2
HBD
116.7
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C8H12N3O5P
MW 261.17
Aromatic Rings 1
Heavy Atoms 17
NP-Likeness 0.08

Activity Summary

EC50 2 meas. best 4.32

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cowpox virus
CHEMBL612672
EC50 4.32 4.32 48300.0 1
Vaccinia virus
CHEMBL613493
EC50 4.3 4.3 50600.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
36961984 10.1021/acs.jmedchem.3c00069 Vaccinia virus 1
36961984 10.1021/acs.jmedchem.3c00069 Cowpox virus 1

Data from ChEMBL 36 via Core Engine