Assay Detail
Functional
CHEMBL5374601
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Cytotoxicity against human T47D cells assessed as inhbition of cell growth measured after 48 hrs by CCK-8 method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.18 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5440773 | — | — | 1 | 6.60 |
| CHEMBL5394958 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5440773 | — | IC50 | = | 252.9 | nM | 6.60 |
| CHEMBL5394958 | — | IC50 | = | 1761.0 | nM | 5.75 |