Assay Detail
Functional
CHEMBL5375671
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human NB4 cells measured after 72 hrs by celltiter96 aqueous non-radioactive cell proliferation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NB-4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel 1,8-Naphthalimide Derivatives As Antitumor Agents and Potent Demethylase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.23 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4567838 | — | — | 1 | 6.10 |
| CHEMBL4572939 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4567838 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL4572939 | — | IC50 | = | 44800.0 | nM | 4.35 |