Assay Detail
Binding
CHEMBL5389468
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Inhibition of human CDC25B
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Microascones, Decahydrofluorene-Class Alkaloids from the Marine-Derived Fungus <i>Microascus</i> sp. SCSIO 41821.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.96 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4469905 | — | — | 1 | 5.22 |
| CHEMBL179166 | SODIUM ORTHOVANAD | — | 1 | 4.70 |
| CHEMBL5411827 | — | — | 1 | - |
| CHEMBL5420456 | — | — | 1 | - |
| CHEMBL5411916 | — | — | 1 | - |
| CHEMBL4447474 | — | — | 1 | - |
| CHEMBL4449755 | — | — | 1 | - |
| CHEMBL5421141 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4469905 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL179166 | SODIUM ORTHOVANAD | IC50 | = | 20100.0 | nM | 4.70 |
| CHEMBL5411827 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL5420456 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL5411916 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4447474 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL4449755 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL5421141 | — | IC50 | > | 200000.0 | nM | - |