Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5500433

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human ZR-75-1 cells assessed as reduction in cell growth measured after 5 days by Celltiter-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type ZR-75-1
Confidence 1 — Organism
Curated By Autocuration

Target

ZR-75-1 (CHEMBL614393)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and clinical application of small-molecule drugs approved to treat prostatic cancer.
Zhang JY, Zhao LJ, Wang YT.
Eur J Med Chem (2023) 262 : 115925 -115925
PubMed 37948954 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.12 7.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1274 NILUTAMIDE 4.0 1 7.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1274 NILUTAMIDE IC50 = 75.0 nM 7.12