Assay Detail
Binding
CHEMBL5501669
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to GST/His-tagged recombinant rat androgen receptor (606 to 902 residues) ligand binding domain expressed in baculovirus expression system assessed as dissociation constant by Biolayer interferometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel selective agents for the degradation of AR/AR-V7 to treat advanced prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.23 | 6.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5559204 | — | — | 1 | 6.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5559204 | — | Kd | = | 590.0 | nM | 6.23 |