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Assay Detail

CHEMBL5505236

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-tumor activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Jurkat
Confidence 1 — Organism
Curated By Autocuration

Target

Jurkat (CHEMBL397)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of Novel 2-Oxoacetamide Derivatives as B3GAT3 Inhibitors for the Treatment of Hepatocellular Carcinoma.
Yin H, Zhang M, Gu C, Li Z, Hao C, Wang J, Tian L, Xu K, Hu X, Ming L, Zhang M, Wang Z, Yang Y, Zhang D, Dai B.
J Med Chem (2024) 67 : 10743 -10773
PubMed 38919032 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.17 5.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5558191 1 5.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5558191 IC50 = 6690.0 nM 5.17