Assay Detail
Functional
CHEMBL5505343
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Trypanocidal activity against bloodstream-stage Trypanosoma brucei measured after 72 hrs by CellTiter-Glo luminescent assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-Activity Study on Substituted, Core-Extended, and Dyad Naphthalene Diimide G-Quadruplex Ligands Leading to Potent Antitrypanosomal Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.33 | 10.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5505832 | — | — | 1 | 10.96 |
| CHEMBL4594805 | — | — | 1 | 10.15 |
| CHEMBL5542708 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5505832 | — | IC50 | = | 0.011 | nM | 10.96 |
| CHEMBL4594805 | — | IC50 | = | 0.07 | nM | 10.15 |
| CHEMBL5542708 | — | IC50 | = | 130.0 | nM | 6.89 |