Assay Detail
Binding
CHEMBL5506269
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SARS CoV-2 main protease
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Replicase polyprotein 1ab (CHEMBL4523582) ↗| Type | SINGLE PROTEIN |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Plant-derived strategies to fight against severe acute respiratory syndrome coronavirus 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.23 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL449782 | CEPHARANTHINE | 2.0 | 1 | 7.00 |
| CHEMBL164 | MYRICETIN | — | 1 | 6.20 |
| CHEMBL8260 | BAICALEIN | 2.0 | 1 | 5.93 |
| CHEMBL9470 | SHIKONIN | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL449782 | CEPHARANTHINE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL164 | MYRICETIN | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL8260 | BAICALEIN | IC50 | = | 1180.0 | nM | 5.93 |
| CHEMBL9470 | SHIKONIN | IC50 | = | 1570.0 | nM | 5.80 |