Assay Detail
Binding
CHEMBL5511701
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Inhibition of YTHDC1 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-Based Design of a Potent and Selective YTHDC1 Ligand.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.85 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5532185 | — | — | 1 | 5.70 |
| CHEMBL5565148 | — | — | 1 | 4.43 |
| CHEMBL5177286 | — | — | 1 | 4.41 |
| CHEMBL5179548 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5532185 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL5565148 | — | IC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL5177286 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL5179548 | — | IC50 | = | 306000.0 | nM | - |