Assay Detail
Binding
CHEMBL5513459
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at AMPK (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
5'-AMP-activated protein kinase catalytic subunit alpha-2 (CHEMBL2116) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting autophagy drug discovery: Targets, indications and development trends.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.70 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL273453 | ALDOSTERONE | 2.0 | 1 | 8.89 |
| CHEMBL5555324 | — | — | 1 | 6.52 |
| CHEMBL4542477 | — | — | 1 | 6.10 |
| CHEMBL450916 | PROANTHOCYANIDIN A1 | — | 1 | 5.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL273453 | ALDOSTERONE | EC50 | = | 1.3 | nM | 8.89 |
| CHEMBL5555324 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4542477 | — | EC50 | = | 800.0 | nM | 6.10 |
| CHEMBL450916 | PROANTHOCYANIDIN A1 | EC50 | = | 5100.0 | nM | 5.29 |