Compound Detail
CHEMBL5555324
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Basic Information
| ChEMBL ID | CHEMBL5555324 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FIZDBNPUFMDGFZ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
293.3
MW (Da)
4.41
ALogP
2
HBA
1
HBD
33.1
PSA (Ų)
0.78
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 CHEMBL2116 | EC50 | 6.52 | 6.52 | 300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | EC50 | = | 300.0 | nM | 6.52 | Agonist activity at AMPK (unknown origin) | 38295689 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38295689 | 10.1016/j.ejmech.2023.116117 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | 1 |
Data from ChEMBL 36 via Core Engine