Assay Detail
Functional
CHEMBL5518288
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Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of targeting nicotinamide phosphoribosyltransferase (NAMPT) for cancer drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.85 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4213004 | — | — | 1 | 8.15 |
| CHEMBL4217940 | — | — | 1 | 7.82 |
| CHEMBL4205098 | — | — | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4213004 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL4217940 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL4205098 | — | IC50 | = | 27.0 | nM | 7.57 |