Assay Detail
ADMET
CHEMBL5518289
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP3A4 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances of targeting nicotinamide phosphoribosyltransferase (NAMPT) for cancer drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.85 | 4.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4208619 | — | — | 1 | 4.97 |
| CHEMBL4204004 | — | — | 1 | 4.80 |
| CHEMBL4209341 | — | — | 1 | 4.77 |
| CHEMBL4082366 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4208619 | — | IC50 | = | 10700.0 | nM | 4.97 |
| CHEMBL4204004 | — | IC50 | = | 15800.0 | nM | 4.80 |
| CHEMBL4209341 | — | IC50 | = | 17100.0 | nM | 4.77 |
| CHEMBL4082366 | — | IC50 | > | 20000.0 | nM | - |