Assay Detail
Binding
CHEMBL5520152
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of UCH-L1 (unknown origin) expressed in Escherichia coli BL21 (DE3)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (CHEMBL6159) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances in the development of deubiquitinases inhibitors as antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.06 | 6.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1241672 | — | — | 1 | 6.09 |
| CHEMBL1241765 | — | — | 1 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1241672 | — | IC50 | = | 810.0 | nM | 6.09 |
| CHEMBL1241765 | — | IC50 | = | 940.0 | nM | 6.03 |