Assay Detail
Binding
CHEMBL5524629
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat hepatocytes CPT1A
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | Hepatocyte |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Carnitine O-palmitoyltransferase 1, liver isoform (CHEMBL3858) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Modulators for palmitoylation of proteins and small molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.92 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2216779 | — | — | 1 | 5.96 |
| CHEMBL2216778 | — | — | 1 | 5.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2216779 | — | IC50 | = | 1090.0 | nM | 5.96 |
| CHEMBL2216778 | — | IC50 | = | 1340.0 | nM | 5.87 |